One of the silliest things I have do as a Palliative physician is to sift through the lists of medications that my patients are on and make the useless ones go away.
For instance, what sense does it make if you are suffering from cancer to take cholesterol lowering medications? Not only is it unnecessary, but they can interfere with chemotherapy and can certainly interfere with the enjoyment of life.
My advice to patients and their families who are in this situation, is to review the medication list with their physician and try to exclude anything that will not benefit them in the "here and now" and for comfort sake.
What good is the statistical chance of decreased stroke 25 years from now when the medications to do that make you miserable or worse, shorten your lifespan interfering with your chemo?
With medications such as the lipid lowering agents, daily aspirin therapy, and the like, once you achieve clinical remission or cure, then you can resume all those medications for long term preventative care.